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Kristian Krøyer, Ulrik Christensen, Michael Larsen, Morten la Cour; Quantification of Metamorphopsia in Patients with Macular Hole. Invest. Ophthalmol. Vis. Sci. 2008;49(9):3741-3746. doi: 10.1167/iovs.07-1452.
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purpose. To describe a novel method for the evaluation of metamorphopsia within the central 10° of the visual field in 55 patients with idiopathic macular hole. The test evaluates the interocular disparity between the two eyes in metamorphopsia.
methods. Semicircular test and reference stimuli of variable diameters were used in a binocular test that measured interocular size disparity between perceptually iseikonic stimuli in subjects with a unilateral macular hole. A group of 11 healthy subjects was used as the reference.
results. In 55 patients with a macular hole, interocular disparity demonstrated a mean value of 0.71° with stimuli in the range 1.0° to 2.5° in diameter. This number declined to 0.41° with stimuli in the range of 9.0° to 10.0° in diameter. Both hole diameter and eccentricity had a significant effect on mean disparity (P < 0.001).
conclusions. The level of metamorphopsia declined as a function of eccentricity and affected the central 10° of visual field. Macular hole size had an independent effect on interocular disparity. These results confirm reports that visuospatial distortion in the presence of macular hole is primarily the result of radial displacement of photoreceptors. (ClinicalTrials.gov number, NCT00302328.)
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