Author Response: Pupil Dynamics and Response Amplitude: Only Size Matters

I was not aware of these studies, but am indebted to Professor Maddess ¹ for bringing to our attention these earlier publications by Semmlow and Stark. ^2,3 These studies and mine ⁴ show that pupil dynamics are scaled according to response amplitude as an intrinsic property of the neuromuscular plant, and so provide no specific additional information about function in the optic nerves, a point that has not been appreciated in many of the publications on pupillometric evaluation of optic neuropathies over the last 40 years.