May 1970
Volume 9, Issue 5
Articles  |   May 1970
Oxygen-Induced Visual Cell Degeneration in the Rabbit
Author Affiliations
    Chief, Joint Laser Safety Team, W1000, Frankford Arsenal, Philadelphia, Pa., 19137
Investigative Ophthalmology & Visual Science May 1970, Vol.9, 372-387. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      GEORGE H. BRESNICK; Oxygen-Induced Visual Cell Degeneration in the Rabbit. Invest. Ophthalmol. Vis. Sci. 1970;9(5):372-387.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

High oxygen concentrations induced visual cell degeneration in albino and pigmented rabbits. The most sensitive cells were located in the area centralis, a zone analogous to the human macula, and characterized by low glycogen content and rich choroidal blood supply. Electron microscopy demonstrated early pathological changes of intracellular membranes followed by total disorganization of visual cells, particularly those with rod-type synapses. DL-alphatocopherol acetate did not prevent visual cell damage.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.