July 1976
Volume 15, Issue 7
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Articles  |   July 1976
Actin filaments in apical projections of the primate pigmented epithelial cell.
Investigative Ophthalmology & Visual Science July 1976, Vol.15, 570-575. doi:https://doi.org/
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      B Burnside, A M Laties; Actin filaments in apical projections of the primate pigmented epithelial cell.. Invest. Ophthalmol. Vis. Sci. 1976;15(7):570-575. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A highly-ordered array of filaments is found within the apical processes of retinal pigmented epithelial cells in monkeys and humans. These filaments, approximately 100 A in diameter and 250 A apart, line the cytoplasmic face of the plasma membrane, in parallel with the long axis of the apical processes. Since these filaments bind rabbit myosin subfrafment-1 to form arrowhead complexes, we conclude that they contain actin. Such membrane-bound actin filaments could have any of several different functions: they could stabilize the apical projections and by so doing play a cytoskeletal role, and/or they could take part in the phagocytosis of shed outer segment discs.

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