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R B Kurzel, R L Heinrikson; On the presence of bilirubin in the ocular humors of premature infants.. Invest. Ophthalmol. Vis. Sci. 1976;15(6):509-512.
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The yellow pigments observed in the ocular humors of premature infants were identified as the plasma pigments bilirubin and oxyhemoglobin. The blood/vitreous humor barrier to bilirubin was estimated to be (1/0.11) for total bilirubin and (1/0.25) for direct-acting bilirubin. Hall method histochemical staining for bilirubin in sections of premature infant eyes was highly positive for the vitreous humor, and suggestive of uptake of bilirubin by the neural-retinal cells.
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