October 1978
Volume 17, Issue 10
Articles  |   October 1978
Variations in acute multifocal histoplasmic choroiditis in the primate.
Investigative Ophthalmology & Visual Science October 1978, Vol.17, 1005-1018. doi:https://doi.org/
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      R E Smith, J I Macy, C Parrett, J Irvine; Variations in acute multifocal histoplasmic choroiditis in the primate.. Invest. Ophthalmol. Vis. Sci. 1978;17(10):1005-1018. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Experimental histoplasmic choroiditis was produced in primates by intracarotid injections of living H. capsulatum organisms. The severity of the choroiditis varied with inoculum size, as well as with site of injection (common carotid vs. internal carotid artery). A reproducible model of histoplasmic choroiditis in primates was produced with an internal carotid injection of 5,000 to 10,000 organisms/lb. The clinical and histopathological course of this acute choroiditis over the first 30 days is presented.


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