October 1978
Volume 17, Issue 10
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Articles  |   October 1978
Sensitizing activity of 9,13-dicis retinal in bleached photoreceptors of the skate.
Investigative Ophthalmology & Visual Science October 1978, Vol.17, 1024-1029. doi:
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      R Crouch, D R Pepperberg; Sensitizing activity of 9,13-dicis retinal in bleached photoreceptors of the skate.. Invest. Ophthalmol. Vis. Sci. 1978;17(10):1024-1029.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

9,13-dicis Retinal was externally applied to photoreceptors of isolated skate retina that previously had been desensitized by bleaching irradiation. This treatment led to a significant lowering of photoreceptor threshold and to the intracellular formation of isorhodopsin II, an artificial visual pigment containing 9,13-dicis retinal as its chromophore. These results suggest that isorhodopsin II can function in situ to promote an increase in the visual sensitivity of skate photoreceptors.

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