July 1978
Volume 17, Issue 7
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Articles  |   July 1978
Localization of beta receptors in the anterior segment of the rat eye by a fluorescent analogue of propranolol.
Investigative Ophthalmology & Visual Science July 1978, Vol.17, 645-651. doi:
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      M Lahav, E Melamed, Z Dafna, D Atlas; Localization of beta receptors in the anterior segment of the rat eye by a fluorescent analogue of propranolol.. Invest. Ophthalmol. Vis. Sci. 1978;17(7):645-651.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A fluorescent analogue of propranolol, 9-AAP, was injected intravenously in order to detect beta-adrenergic receptors in the anterior segment of the albino rat eye. Specific 9-AAP fluorescence was noted along cell membranes of the ciliary epithelium and to lesser extent in the walls of blood vessels in the ciliary processes and episclera at the limbus. The iris showed maximum 9-AAP binding in the region of the sphincter muscle. These data suggest that 9-AAP may label beta receptors in the anterior segment of the rat eye.

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