August 1978
Volume 17, Issue 8
Articles  |   August 1978
Congenital stationary night blindness: an animal model.
Investigative Ophthalmology & Visual Science August 1978, Vol.17, 788-795. doi:
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      D A Witzel, E L Smith, R D Wilson, G D Aguirre; Congenital stationary night blindness: an animal model.. Invest. Ophthalmol. Vis. Sci. 1978;17(8):788-795.

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      © ARVO (1962-2015); The Authors (2016-present)

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Electroretinographic studies of myctalopic Appaloosa horses demonstrated photopic and scotopic abnormalities similar to those in humans with congenital stationary night blindness (CSNB) of the Schubert-Bornschein type. The phototopic abnormalities consisted of reduced b-wave amplitudes and slower than normal b-wave implict time. The dark-adapted ERG's consisted of a simple negative potential; the scotopic b-wave was nonrecordable. However, a normal c-wave was present in the dark-adapted response. Histologic studies demonstrated no structural abnormalities that could explain the functional defect.


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