August 1978
Volume 17, Issue 8
Articles  |   August 1978
Rhodopsin and visual threshold in retinitis pigmentosa.
Investigative Ophthalmology & Visual Science August 1978, Vol.17, 735-745. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      H Ripps, K P Brin, R A Weale; Rhodopsin and visual threshold in retinitis pigmentosa.. Invest. Ophthalmol. Vis. Sci. 1978;17(8):735-745.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Rhodopsin kinetics and visual threshold were determined in three subjects with a dominant form of retinitis pigmentosa. The retinal areas studied showed varying loss of sensitivity, which correlated well with the reduction in the measured density of rhodopsin in the test region. Rhodopsin photosensitivity was normal, and there was no evidence that either rhodopsin or the cone pigments regenerated more rapidly than normal. The findings in these cases of retinitis pigmentosa, when compared with the threshold changes induced by vitamin A deficiency or photic bleaching, suggest that the disease produces an imbalance between disc removal and new disc formation, which results in a progressive shortening of the photoreceptor outer segments and, eventually, in their complete disappearance.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.