July 1978
Volume 17, Issue 7
Free
Articles  |   July 1978
Photosensitive cataractogens, chlorpromazine and methoxypsoralen, cause DNA repair synthesis in lens epithelial cells.
Investigative Ophthalmology & Visual Science July 1978, Vol.17, 687-691. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J G Jose, K L Yielding; Photosensitive cataractogens, chlorpromazine and methoxypsoralen, cause DNA repair synthesis in lens epithelial cells.. Invest. Ophthalmol. Vis. Sci. 1978;17(7):687-691.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
This content is PDF only. Please click on the PDF icon to access.
Abstract

Autoradiographic techniques showed that photoactivation of methoxypsoralen opr chlorpomazine caused diffuse nuclear labeling of lens epithelial cells by thymidine. Chlorpromazine and light also induced thymidine incorporation into lymphocytes, whereas light or drug alone did not cause unscheduled DNA synthesis.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×