August 1981
Volume 21, Issue 2
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Articles  |   August 1981
A corneal micropocket assay for angiogenesis in the rat eye.
Investigative Ophthalmology & Visual Science August 1981, Vol.21, 351-354. doi:
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      G A Fournier, G A Lutty, S Watt, A Fenselau, A Patz; A corneal micropocket assay for angiogenesis in the rat eye.. Invest. Ophthalmol. Vis. Sci. 1981;21(2):351-354.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A corneal micropocket assay for angiogenesis in the rat eye is described in detail. With our test system, a partially purified, low molecular-weight endothelial cell growth stimulatory factor isolated from the Walker 256 rat carcinosarcoma is demonstrated to have potent angiogenic activity in vivo. The advantages and applications of our rat corneal assay are discussed.

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