September 1981
Volume 21, Issue 3
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Articles  |   September 1981
Sex chromatin of donor corneal epithelium in rabbits.
Investigative Ophthalmology & Visual Science September 1981, Vol.21, 434-441. doi:
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      S Kinoshita, J Friend, R A Thoft; Sex chromatin of donor corneal epithelium in rabbits.. Invest. Ophthalmol. Vis. Sci. 1981;21(3):434-441.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The survival of donor corneal epithelium was investigated in rabbits after they received unilateral 8 mm diameter lamellar keratoplasties with living donor tissue of a different sex from the host. Three weeks, 6 weeks, and 12 weeks postoperatively, cultured corneal epithelia, grown from 5 mm diameter central buttons, the adjacent 0.75 mm wide donor rings, the peripheral 10 to 13 mm diameter rings, and 5 mm diameter central host buttons were used for sex-chromatin analysis. The results indicated that some of the donor corneal epithelium survived up to 12 weeks postoperatively. Even in the absence of overt epithelial rejection, however, a time-dependent decrease of donor corneal epithelium and simultaneous invasion of host corneal epithelium were demonstrated.

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