March 1982
Volume 22, Issue 3
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Articles  |   March 1982
Effects of topical 10% ascorbate solution on established corneal ulcers after severe alkali burns.
Investigative Ophthalmology & Visual Science March 1982, Vol.22, 382-385. doi:
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      R R Pfister, C A Paterson, S A Hayes; Effects of topical 10% ascorbate solution on established corneal ulcers after severe alkali burns.. Invest. Ophthalmol. Vis. Sci. 1982;22(3):382-385.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

When established corneal ulcers induced by alkali burning were treated with 10% ascorbate drops, no perforation occurred, in contrast to a 25% incidence in the control group. If perforations and descemetoceles were grouped together, these difference became insignificant (i.e., 14.2% ascorbate-treated vs. 25% control). Prolongation of descemetocele presence without perforation in the ascorbate-treated group indicated some therapeutic effect. We conclude that topical ascorbate does not substantially alter the outcome of established corneal ulcers.

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