Purchase this article with an account.
G R McCarty, B Schwartz; Increased concentration of glucocorticoid receptors in rabbit iris--ciliary body compared to rabbit liver.. Invest. Ophthalmol. Vis. Sci. 1982;23(4):525-528.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Dexamethasone binding to both rabbit iris-ciliary body and rabbit liver glucocorticoid receptors was compared by means of a batch assay in which the binding components were adsorbed to hydroxylapatite. The results showed that homogenates of both the rabbit iris-ciliary body and the rabbit liver contained a single class of high-affinity receptors. Binding affinity was virtually identical for the two receptors. A comparison of total binding sites in homogenates of the iris-ciliary body and the liver revealed that the iris-ciliary body glucocorticoid receptor was present in nearly twice the concentration of the hepatic receptor.
This PDF is available to Subscribers Only