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G R McCarty, B Schwartz; Increased concentration of glucocorticoid receptors in rabbit iris--ciliary body compared to rabbit liver.. Invest. Ophthalmol. Vis. Sci. 1982;23(4):525-528. doi: https://doi.org/.
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Dexamethasone binding to both rabbit iris-ciliary body and rabbit liver glucocorticoid receptors was compared by means of a batch assay in which the binding components were adsorbed to hydroxylapatite. The results showed that homogenates of both the rabbit iris-ciliary body and the rabbit liver contained a single class of high-affinity receptors. Binding affinity was virtually identical for the two receptors. A comparison of total binding sites in homogenates of the iris-ciliary body and the liver revealed that the iris-ciliary body glucocorticoid receptor was present in nearly twice the concentration of the hepatic receptor.
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