November 1982
Volume 23, Issue 5
Articles  |   November 1982
Substance P-immunoreactive nerves in the human cornea and iris.
Investigative Ophthalmology & Visual Science November 1982, Vol.23, 671-674. doi:
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      K Tervo, T Tervo, L Eränkö, A Vannas, A C Cuello, O Eränkö; Substance P-immunoreactive nerves in the human cornea and iris.. Invest. Ophthalmol. Vis. Sci. 1982;23(5):671-674. doi:

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      © ARVO (1962-2015); The Authors (2016-present)

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Human corneas and irides obtained from corneal surgery or sector iridectomies were processed according to the indirect immunofluorescence technique for the demonstration of substance P (SP) immunofluorescence by means of a monoclonal SP antibody. SP immunofluorescence was observed in varicose fibers of the corneal epithelium and nerve trunks in the corneal stroma. SP-immunoreactive nerve fibers in the iris were detected mainly in the pupillary margin in both dilator and sphincter areas.


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