October 1984
Volume 25, Issue 10
Articles  |   October 1984
Nonlysozyme antibacterial factor in human tears. Fact or fiction?
Investigative Ophthalmology & Visual Science October 1984, Vol.25, 1156-1160. doi:
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      P T Janssen, H L Muytjens, O P van Bijsterveld; Nonlysozyme antibacterial factor in human tears. Fact or fiction?. Invest. Ophthalmol. Vis. Sci. 1984;25(10):1156-1160.

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      © ARVO (1962-2015); The Authors (2016-present)

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The existence of nonlysozyme antibacterial activity in tear fluid was reinvestigated. Tear fluid was fractionated by ultrafiltration and affinity chromatography. The antibacterial activity, detected in native tear fluid, coincided with the presence of lysozyme in the fractions. No antibacterial activity could be detected by agar diffusion in the fractions that should contain the low molecular mass antibacterial factors of tear fluid, reported in the literature.


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