April 1985
Volume 26, Issue 4
Free
Articles  |   April 1985
Immunology of corneal allograft rejection: HLA-DR antigens on human corneal cells.
Investigative Ophthalmology & Visual Science April 1985, Vol.26, 571-574. doi:
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      E Young, W J Stark, R A Prendergast; Immunology of corneal allograft rejection: HLA-DR antigens on human corneal cells.. Invest. Ophthalmol. Vis. Sci. 1985;26(4):571-574.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Human stromal and endothelial cultures were established from corneas obtained from the Maryland Eye Bank. Cultures were incubated in the presence of human gamma interferon for 4 days, trypsinized, washed, and then stained with a monoclonal reagent specific for human Class II (HLA-DR) antigens. Under these conditions, 100% of human corneal endothelial cells and 40 to 70% human corneal stromal cells expressed HLA-DR antigens.

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