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E Young, W J Stark, R A Prendergast; Immunology of corneal allograft rejection: HLA-DR antigens on human corneal cells.. Invest. Ophthalmol. Vis. Sci. 1985;26(4):571-574.
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Human stromal and endothelial cultures were established from corneas obtained from the Maryland Eye Bank. Cultures were incubated in the presence of human gamma interferon for 4 days, trypsinized, washed, and then stained with a monoclonal reagent specific for human Class II (HLA-DR) antigens. Under these conditions, 100% of human corneal endothelial cells and 40 to 70% human corneal stromal cells expressed HLA-DR antigens.
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