October 1986
Volume 27, Issue 10
Articles  |   October 1986
Lectin binding to pseudoexfoliative material and the ocular zonules.
Investigative Ophthalmology & Visual Science October 1986, Vol.27, 1516-1521. doi:
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      B W Streeten, S A Gibson, Z Y Li; Lectin binding to pseudoexfoliative material and the ocular zonules.. Invest. Ophthalmol. Vis. Sci. 1986;27(10):1516-1521.

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      © ARVO (1962-2015); The Authors (2016-present)

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Lectin staining of pseudoexfoliative material on the lens capsule, zonules, and iris showed the presence of the beta-D-galactose (1-3) galactosamine sequence, alpha-D-galactosamine, beta-D-galactose, beta-(1-4)-D-glucosamine, and terminal sialic acid. Mono and difucosyl binding sites were also found. The likelihood that the lectins were binding to two different galactosamine-containing moieties was supported by their different distributions in the photoreceptors. These affinities suggest a complex carbohydrate composition in pseudoexfoliative material, with both O-linked sialomucin-type and N-linked oligosaccharide chains.


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