April 1987
Volume 28, Issue 4
Articles  |   April 1987
Electron microscopy and HLA expression of a new cell line of retinoblastoma.
Investigative Ophthalmology & Visual Science April 1987, Vol.28, 690-699. doi:https://doi.org/
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      G A Fournier, D N Sang, D M Albert, J L Craft; Electron microscopy and HLA expression of a new cell line of retinoblastoma.. Invest. Ophthalmol. Vis. Sci. 1987;28(4):690-699. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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A new continuous retinoblastoma cell line (Rb 355-7) derived from a nonfamilial unilaterally-affected child was studied morphologically and with regard to HLA expression. The tumor was compared with two older and widely studied cell lines, the Y-79 and WERI-Rb1 strains. The Rb 355-7 line grew in tissue culture in clusters and chains. Its doubling time was calculated to be 4.4 days. In contrast to the Y-79 and WERI-Rb1 cell lines, the Rb 355-7 showed a paucity of HLA expression.


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