October 1989
Volume 30, Issue 10
Free
Articles  |   October 1989
Initial characterization of lens beta-adrenergic receptors.
Author Affiliations
  • M E Ireland
    Department of Anatomy/Cell Biology, Wayne State University, School of Medicine, Detroit, Michigan.
  • L A Jacks
    Department of Anatomy/Cell Biology, Wayne State University, School of Medicine, Detroit, Michigan.
Investigative Ophthalmology & Visual Science October 1989, Vol.30, 2190-2194. doi:
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      M E Ireland, L A Jacks; Initial characterization of lens beta-adrenergic receptors.. Invest. Ophthalmol. Vis. Sci. 1989;30(10):2190-2194.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Crude plasma membranes were prepared from chick lens epithelial and fiber cells and assayed for specific binding of the beta-adrenergic antagonist dihydroalprenolol. Both membranes specifically bound the ligand, with the epithelial membranes exhibiting a greater number of higher affinity sites. This is the first demonstration of lens beta-adrenergic receptors using this type of assay and the first direct demonstration of beta-adrenergic receptors in lens fiber cells.

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