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M E Ireland, L A Jacks; Initial characterization of lens beta-adrenergic receptors.. Invest. Ophthalmol. Vis. Sci. 1989;30(10):2190-2194.
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Crude plasma membranes were prepared from chick lens epithelial and fiber cells and assayed for specific binding of the beta-adrenergic antagonist dihydroalprenolol. Both membranes specifically bound the ligand, with the epithelial membranes exhibiting a greater number of higher affinity sites. This is the first demonstration of lens beta-adrenergic receptors using this type of assay and the first direct demonstration of beta-adrenergic receptors in lens fiber cells.
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