April 1991
Volume 32, Issue 5
Articles  |   April 1991
Dysplastic canine retinal morphogenesis.
Author Affiliations
  • H E Whiteley
    Department of Veterinary Pathobiology, University of Illinois, Urbana 61801.
Investigative Ophthalmology & Visual Science April 1991, Vol.32, 1492-1498. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      H E Whiteley; Dysplastic canine retinal morphogenesis.. Invest. Ophthalmol. Vis. Sci. 1991;32(5):1492-1498.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

Retinal dysplasia is a failure in normal retinal development. The morphologic sequence of the dysplastic processes was examined in fetuses and neonates from dogs affected with an inherited form of retinal dysplasia. The dysplastic change has its onset at 45-50 days' gestation and is most prominent in the dorsal peripapillary retina. Morphologic characteristics of involved sensory retina include the focal loss of cell junctions forming the external limiting membrane, folding of the sensory retina, disorganized proliferation of neuroblasts in the retina and subretinal space, and formation of rosettes composed of multiple layers of neuroblasts. These morphologic changes suggest that there is an intrinsic abnormality of neural retinal differentiation.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.