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M A Sandberg, H Lee, G P Matthews, A R Gaudio; Relationship of oscillatory potential amplitude to A-wave slope over a range of flash luminances in normal subjects.. Invest. Ophthalmol. Vis. Sci. 1991;32(5):1508-1516.
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© ARVO (1962-2015); The Authors (2016-present)
The effect of flash luminance on the relationship of oscillatory potential (OP) amplitude, as a measurement of inner retinal function, to a-wave slope, as a measurement of photoreceptor function, was evaluated in full-field electroretinograms recorded from normal subjects. The ratio of OP amplitude to a-wave slope was found to be independent of flash luminance over a 3000-fold luminance range. This finding raises the possibility that a reduction in the ratio of OP amplitude to a-wave slope in eyes with media opacities may be used as a sign of inner retinal malfunction. Selected cases are presented to illustrate application of this approach.
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