June 1992
Volume 33, Issue 7
Free
Articles  |   June 1992
Pattern-reversal electroretinographic acuity in untreated eyes with subfoveal neovascular membranes.
Author Affiliations
  • D G Birch
    Retina Foundation of the Southwest, Dallas, TX 75231.
  • J L Anderson
    Retina Foundation of the Southwest, Dallas, TX 75231.
  • G E Fish
    Retina Foundation of the Southwest, Dallas, TX 75231.
  • B F Jost
    Retina Foundation of the Southwest, Dallas, TX 75231.
Investigative Ophthalmology & Visual Science June 1992, Vol.33, 2097-2104. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      D G Birch, J L Anderson, G E Fish, B F Jost; Pattern-reversal electroretinographic acuity in untreated eyes with subfoveal neovascular membranes.. Invest. Ophthalmol. Vis. Sci. 1992;33(7):2097-2104.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

To define further the natural history of visual loss in eyes with age-related macular degeneration (ARMD) complicated by a subfoveal neovascular membrane, pattern-reversal electroretinograms (ERGs) were obtained from patients randomized to no treatment at the Dallas center of the Macular Photocoagulation Study (Texas Retina Associates). Study eyes (n = 20) were tested during the initial visit and at 3-, 6-, and 12-month follow-up visits. Responses were obtained to phase-alternating checkerboards of varying check size. Extrapolation of the best-fit regression line relating the logarithm of the check size to amplitude was used to determine "retinal" acuity (log MAR). The pattern-reversal ERG acuity rating (100 - [50 x log MAR]) was derived for each visit. Pattern-reversal ERG acuity ratings for all patients across visits were correlated significantly with visual acuity ratings derived from the Bailey-Lovie chart (r = 0.61, P less than 0.001) and inversely related to neovascular membrane area (r = -0.55, P less than 0.001). During 1 yr of follow-up, pattern-reversal acuity ratings dropped from 53 to 12, corresponding to an average decrease of approximately 0.2 octaves/month. These results suggest that the pattern-reversal ERG, which samples the resolving power of the central 20 degrees, is a sensitive index of visual loss in age-related macular degeneration.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×