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Maria Letizia Salvetat, Marco Zeppieri, Lucia Parisi, Paolo Brusini; Rarebit Perimetry in Normal Subjects: Test–Retest Variability, Learning Effect, Normative Range, Influence of Optical Defocus, and Cataract Extraction. Invest. Ophthalmol. Vis. Sci. 2007;48(11):5320-5331. doi: https://doi.org/10.1167/iovs.06-1495.
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© ARVO (1962-2015); The Authors (2016-present)
purpose. To study normative ranges, learning effect (LE), test–retest variability (TRV), and influence of blur and cataract in normal subjects by using rarebit perimetry (RBP).
methods. Seventy-five normal subjects underwent visual field (VF) testing with standard automated perimetry (SAP) and RBP. LE and TRV for RBP were assessed in repeated examinations conducted on four different days. LE was evaluated by comparing results from the first with those of the other three sessions. TRV was studied by calculating differences between retest for each combination of single tests. The blur effect was evaluated by repeated tests with spherical lenses added to the optimum refractive correction (±1.00 to ±6.00 D). The cataract effect was studied in 23 subjects who underwent RBP 1 week before and 1 month after cataract surgery. Mean hit rate (MHR) and mean miss rate (MMR) were analyzed for single areas and test duration.
results. The mean MHR was 91% ± 5.7% (range, 78%–99%); the mean MMR ranged from 4.0% to 13.8%. MHR significantly decreased with age (mean, 0.21%/year). Mean test time was 268 ± 34.1 seconds. No significant LE was observed. TRV was significantly higher in the central VF zone and in elderly subjects. MHR increased with refractive blur and significantly decreased after cataract surgery. Effects of blur and cataract extraction were significantly higher in the central VF zone, especially in elderly subjects.
conclusions. RBP is a rapid and easily accessible VF test. RBP testing did not show a significant LE; however, inter- and intrasubject variability were consistent. Blur and media opacities may give false-positive results in RBP, especially in the central VF, and should be considered.
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