April 2010
Volume 51, Issue 4
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Erratum  |   April 2010
Correction for Maldonado et al., Optimizing Hand-Held Spectral Domain Optical Coherence Tomography Imaging for Neonates, Infants and Children
Investigative Ophthalmology & Visual Science April 2010, Vol.51, 2300-2301. doi:10.1167/iovs.09-4403a
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      Correction for Maldonado et al., Optimizing Hand-Held Spectral Domain Optical Coherence Tomography Imaging for Neonates, Infants and Children. Invest. Ophthalmol. Vis. Sci. 2010;51(4):2300-2301. doi: 10.1167/iovs.09-4403a.

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Erratum in : “Optimizing Hand-Held Spectral Domain Optical Coherence Tomography Imaging for Neonates, Infants and Children” by Ramiro S. Maldonado, Joseph A. Izatt, Neeru Sarin, David K. Wallace, Sharon Freedman, C. M. Cotten, and Cynthia Toth (Invest Ophthalmol Vis Sci. Published online in Recently Accepted Papers January 13, http://www.iovs.org/cgi/content/abstract/iovs.09-4403v1) doi:10.1167/iovs.09-4403 
After the early version of the article was published, the authors were informed by the manufacturer that the retinal scan length settings of the hand-held SD OCT unit were incorrect. The resulting corrections are listed below and will be incorporated into the final published version of the article. 
In the Methods, the following paragraph should be inserted between the first and second paragraphs: 
On February 4, 2010, the manufacturer (Bioptigen Inc.) notified us that the retinal scan length settings for this hand held SD OCT unit were in error; and that each lateral scan setting label on this particular system, created a scan that was 68% of the labeled length. Therefore, all scan lengths (both x and y dimensions) recorded off the unit had to be multiplied by the 0.68 correction factor to represent the actual scan lengths. These corrections have been applied, and thus many scan sizes in this manuscript appear as decimal portions of millimeters, e.g. a 6.8 X 6.8 mm scan. 
The last two sentences in the fourth paragraph of the Results should read: 
For example, in the 32-week PMA infant each millimeter of presumed scan length would actually be 0.629 mm at the retina in this eye (62.9% of the adult eye). Therefore performing a 10 mm retinal scan (set for an adult eye) would result in a 6.3 mm retinal scan in this infant eye. 
In the Results, under the subheading “Correction for different lateral magnification in the pediatric eye,” the two sentences below the first formula should read: 
For example in figure 5(A-B) a 6.8 X 6.8 mm volumetric scan is projected onto the retina of an 8-month-old patient (AXL = 19.2 mm). To correct the lateral dimension: 
SLOR = (19.2 mm / 24 mm) x 6.8  
SLOR = 5.4 mm  
The next equation in that section should be: 
A-scans/B-scan = (pediatric AXL mm / 24 mm) x (Scan length mm) x selected number of A-scans per mm. 
The Figure 4 legend should read: 
Figure 4. SD OCT images with (A, B) and without vignetting (C-F) from incorrect reference arm length. Fig. A and B are from a 6.8 X 6.8 mm volumetric scan of a 38 week PMA infant obtained without reference arm correction, focus or scan density correction. After reference arm correction, the 10.9 X 10.9 mm scan from a 35 week PMA (C-D) and of a 47-week PMA infant (E & F) show a decrease in vignetting. The summed-voxel projection (SVP) demonstrates the loss of peripheral image in A compared to when reference arm is correct (C & E). 
The Figure 5 legend should read: 
Figure 5. Retinal field of view and magnification with SD OCT in an infant. Images A-C were of the right eye at 8 months and C shows the projection of the SD OCT imaged area on the Retcam photograph. Images D-G show additional SD OCT imaging of the same eye at 12 months. The left column shows the SVP retinal image with a selected B-scan in the middle column (corresponding to the green line in the SVP): (A-B) at high magnification, 6.8 X 6.8 scan projecting to 5.4 X 5.4 mm scan length on retina (80% of the adult), (D-E) moderate magnification and wider field of view, 10.9 X 10.9 mm scan projecting to 8.7 x 8.7 mm scan length on retina, and (F-G) even wider field of view, 13.6 X 13.6 mm volumetric scan projecting to 10.9 x 10.9 mm scan length (38 degrees) on retina. Note that with SD OCT imaging of a large area, the scan area is limited by the pupil and vignetting occurs as in F. 
The corrected Table 3 appears below: 
Table 3.
 
Standard Reference Table for Axial Length, Refractive Error, Reference Arm Posistion, and A-scans per B-scan by age, with an Example of a 10-mm Adult scan
Table 3.
 
Standard Reference Table for Axial Length, Refractive Error, Reference Arm Posistion, and A-scans per B-scan by age, with an Example of a 10-mm Adult scan
Citation: Maldonado RS, Izatt JA, Sarin N, Wallace DK, Freedman S, Cotten CM, Toth C. Erratum in: Optimizing hand-held spectral domain optical coherence tomography imaging for neonates, infants and children. Invest Ophthalmol Vis Sci. Published online in Recently Accepted Papers January 13, 2010. http://www.iovs.org/cgi/content/abstract/iovs.09-4403v1. doi:10.1167/iovs.09-4403a 
Table 3.
 
Standard Reference Table for Axial Length, Refractive Error, Reference Arm Posistion, and A-scans per B-scan by age, with an Example of a 10-mm Adult scan
Table 3.
 
Standard Reference Table for Axial Length, Refractive Error, Reference Arm Posistion, and A-scans per B-scan by age, with an Example of a 10-mm Adult scan
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