Right eye images of a 58-year-old woman with type 2 idiopathic MacTel (stage 3) who had a Snellen equivalent BCVA of 20/32. All panels are the same type of image as that in
Figure 1. (
A) A fundus photograph demonstrating crystalline deposits, dilated and blunted vessels, and graying of the macula of the retina. (
B) An FA image illustrating a network of retinal telangiectasis. Leakage is predominantly temporal with some leakage superior to the fovea. (
C) An FAF image showing slightly increased levels of FAF signaling in the fovea. (
D) A CBR image demonstrating a ring-like area of increased parafoveal reflectance. (
E) An MP image showing a parafoveal scotoma predominantly superior and temporal to the fovea. (
F) An infrared image indicating the scan direction and size in (
G) and (
H), as in
Figure 1. (
G,
H) SD-OCT images. (
G) A horizontal line scan through the center of the fovea, taken in the direction of the
horizontal arrow in image (
F), showing that the outer retinal layers have almost disappeared, and that the inner retinal layers are resting on the outer retina. The IS/OS is disrupted temporal to the center of the fovea (between the
blue arrows). (
H) A vertical line scan through the center of the fovea, taken in the direction of the
vertical arrow in (
F), demonstrating the outer retinal defect in the fovea (
arrowhead) and the irregularity of the IS/OS superior to the center of the fovea (between the
blue arrows). Scale bar, 1000 μm. (
I) AO-SLO images of the area indicated by the
white box in (
F) and
double-headed arrows in (
G) and (
H) showing ring-like dark regions (
yellow arrows) surrounded by small dark patches (
red arrows). Dark regions are mainly observed superior and temporal to the center of the fovea corresponding to the hyperfluorescent area (
B), the area of IS/OS disruption (
G and
H), and the area of decreased retinal sensitivity (
E). The areas wherein these features appear on various images are smaller than the area of increased reflectance in the CBR image (
D). Note that small, patchy, dark regions are observed even inferior to the center of the fovea where no leakage is seen on FA. The
asterisk indicates the fixation point.
Middle: High-magnification views of the areas outlined by the
large white box (
left) and
yellow box (
right).
Bottom: High-magnification views of the areas outlined by the
white boxes (a:
left, b:
middle, c:
right).