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Hiroko Terasaki, Yozo Miyake, Ryoji Nomura, Masayuki Horiguchi, Satoshi Suzuki, Mineo Kondo; Blue-on-Yellow Perimetry in the Complete Type of Congenital Stationary Night Blindness. Invest. Ophthalmol. Vis. Sci. 1999;40(11):2761-2764.
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purpose. To resolve the discrepancy between nonrecordable full-field short
wavelength cone electroretinograms (S-cone ERGs) and the presence of
normal color vision in patients with the complete type of congenital
stationary night blindness (CSNB1).
methods. Conventional white-on-white (W-W) perimetry, blue-on-yellow (B-Y)
perimetry, and the Farnsworth–Munsell 100-hue test were performed in
five patients with CSNB1. Diagnosis of CSNB1 was made by clinical and
electrophysiological examinations. Twelve normal, age-matched control
subjects and an additional 7 normal, highly myopic subjects were
results. Color vision was normal in all the CSNB1 patients by the
Farnsworth–Munsell 100-hue test. B-Y perimetry demonstrated that blue
cone sensitivity in CSNB1 was normal in the fixation area, but the mean
sensitivities of the entire 60° field, the central 0°-to-15°, and
15°-to-30° ring were significantly decreased compared with the
normal and myopic subjects. The sensitivity difference between
15°-to-30° and 0°-to-15° in B-Y perimetry increased
significantly in CSNB1 compared with both normal and myopic control
conclusions. Our perimetric results demonstrated that the S-cone function in CSNB1
is preserved only in the fovea and becomes abnormal toward the
peripheral retina. This accounts for the normal color vision that tests
mainly foveal function and the nonrecordable S-cone ERGs that arise
mainly from peripheral retina.
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