Purchase this article with an account.
Mineo Kondo, Yozo Miyake, Chang-Hua Piao, Atsuhiro Tanikawa, Masayuki Horiguchi, Hiroko Terasaki; Amplitude Increase of the Multifocal Electroretinogram during Light Adaptation. Invest. Ophthalmol. Vis. Sci. 1999;40(11):2633-2637.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
purpose. To determine using the multifocal ERG technique whether there are any
regional differences in the increase in the amplitude of cone
electroretinograms (ERGs) during light adaptation.
methods. Multifocal ERGs were recorded with the Visual Evoked Response Imaging
System from five normal subjects. Thirty-seven hexagonal stimulus
elements and a recording time of 60 seconds were used. After 20 minutes
of dark adaptation, multifocal ERGs were repeatedly recorded every 2
minutes over a period of 16 minutes. The amplitudes of the multifocal
ERGs at different eccentricities were compared during the 16 minutes of
results. During the 16 minutes of light adaptation, the summed responses of the
multifocal ERGs increased in amplitude an average of 36% and 47% for
the negative and positive components, respectively. The magnitude of
increase was minimal in the central retina at 22% and was
significantly larger in the peripheral retina at 58%. The implicit
time was slightly increased (<4%) with light adaptation, but there
were no regional differences.
conclusions. The results demonstrated that there are topographic variations in the
amplitude increase of cone ERGs during light adaptation. This
topographic variation indicates that the mechanism for the increase
must be based on known regional differences in the
This PDF is available to Subscribers Only