Insulin levels in the retina after topical administration in diabetic
rats. * P < 0.0002, P <
0.004, P < 0.005, P < 0.00001, and P < 0.002 for the 20-, 60-, 90-, 180-, and 300-minute
ipsilateral retinas, respectively, compared with baseline, and P < 0.02 for the 60-minute contralateral retinas
compared with baseline. Sample sizes were 32, 3, 3, 19, 8, 6, 6, 6, 4,
and 3 for the baseline and 10-, 15-, 20-, 60-, 90-, 180-, 300-, 480-,
and 960-minute time points, respectively, in the ipsilateral eye, and
31, 3, 3, 15, 8, 6, 6, 9, 4, and 4 for the baseline, 10-, 15-, 20-,
60-, 90-, 180-, 300-, 480-, and 960-minute time points, respectively,
in the contralateral eye.