Immune response | | | |
AA946503 | Lcn2, lipocalin 2 | 3.8 | 25.9 |
X13044 | Cd74 antigen | 6.3 | 19.6 |
X71127 | C1qb complement component 1 | 10.4, * | 15.7 |
U17919 | Aif1, allograft inflammatory factor 1 | 5.0 | 10.5, * |
X52477 | C3, complement component 3 | 8.5, * | 10.0 |
M22670 | Alpha-2-macroglobulin | 3.2 | 9.2 |
M15562 | MHC class II RT1.u-D-alpha chain | 5.6 | 8.4 |
J02962 | Lgals3, IgE binding protein | 2.7 | 7.9 |
AF025308 | MHC class 1b antigen (RT1.Cl) | — | 6.5, * |
AA891944 | Interferon gamma induced GTPase | 2.6 | 5.9, * |
D88250 | C1s, complement component 1, s subcomponent | — | 4.7, * |
X73371 | Fcgr2, immunoglobulin gamma FC region receptor II | 2.5, * | 4.5 |
M32062 | Fcgr3, Fc receptor, IgG, low affinity III | 2.0, * | 4.3 |
X61381 | Interferon-induced | 2.2 | 4.2 |
AA799803 | Complement component 1r | 2.6, * | 3.5, * |
A1170268 | B2m, beta-2-microglobulin | 2.8 | 2.6 |
M24324 | RT1Aw2, RT1 class Ib (u haplotype) | — | 2.5, * |
L40362 | RT1Aw2, RT1 class Ib (C-type) | — | 2.3, * |
M31018 | RT1Aw2, RT1 class Ib (Aa alpha-chain) | — | 2.2, * |
K02815 | Btnl2, butyrophilin-like 2 | 2.5 | — |
Cytoskeleton and related proteins | | | |
AF28784 | Gfap | 4.5 | 10.6 |
M83107 | Tagln, transgelin | — | 7.6 |
AA892333 | Tuba1, alpha-tubulin | — | 6.7, * |
U59241 | Tmod1, E-tropomodulin | — | 2.8, * |
AF083269 | Arpc1b, actin related protein 2/3 complex | — | 2.5 |
X62952 | Vim, vimentin | — | 2.6 |
X54617 | Myosin regulatory light chain | — | 2.3 |
AA818677 | Nefh, neurofilament, heavy polypeptide | −2.0 | −8.5, * |
AF031880 | Nfl, neurofilament, light polypeptide | — | −4.0 |
Z12152 | Nef3, neurofilament 3, medium | — | −3.8, * |
M73049 | Alpha-internexin alpha | — | −2.0, * |
Proteases and their inhibitors | | | |
AI169327 | Timp1, tissue inhibitor of metalloproteinase 1 | 7.5, * | 45.8, * |
D00753 | Spin2c, serine protease inhibitor | — | 9.2 |
AA800318 | Ser/Cys proteinase inhibitor (complement comp. 1 inhibitor) | 2.9 | 3.8, * |
X02601 | Mmp3, matrix metalloproteinase 3 | — | 3.5, * |
D90404 | Ctsc, cathepsin C | — | 3.4, * |
S85184 | Cathepsin L | — | 2.4, * |
M23697 | Plat, plasminogen activator | — | 2.0, * |
Receptors and ligands | | | |
U59510 | Endothelin-2 | — | 8.8 |
AA933181 | Tslc1, tumor suppressor | — | 3.6, * |
J05122 | Bzrp, benzodiazepin receptor | — | 3.3 |
S65355 | Endothelin receptor | — | 2.3, * |
Transcription factors | | | |
M65149 | Cebpd, CCAAT/enhancer binding, protein (C/EBP) delta | 3.0 | 8.1 |
AF030089 | Ania4, activity and neurotransmitter-induced | 2.2 | 7.1 |
X54686 | junB | — | 5.3, * |
L16995 | Add1 | — | 4.3, * |
AA945867 | c-jun | — | 4.0 |
AF023087 | Egr1, early growth response 1 | 2.2 | 3.8, * |
L23148 | Id1, inhibitor of DNA binding 1 | — | 3.8, * |
AI237535 | Litaf, LPS-induced TNF-alpha factor | 2.1 | 3.8 |
Extracellular matrix and secreted glycoproteins | | | |
U75929 | Sparc, secreted acidic cystein-rich glycoprotein | — | 6.5 |
X82152 | Fmod, fibromodulin | — | 3.8, * |
AA799803 | Ladinin 1 | — | 3.6, * |
X05834 | Fibronectin | — | 2.9 |
AI012030 | Mgp, matrix Gla protein | — | 2.6 |
AA894092 | Osteoblast-specific factor, related to fascilin | — | 2.6, * |
M64733 | Trmp-2 | 2.1, * | 2.4 |
Accession No. | Gene Name | Multiples of Change | |
| | Early Changes 8 Days | Late Changes 35 Days |
Miscellaneous and unknown | | | |
AA892522 | Novel | — | 3.9 |
X56325 | 2-alpha-1 globin | — | 3.2, * |
U92081 | Epithelial cell transmembrane protein antigen precursor (RT140) | — | 2.8, * |
AF017437 | Cd47, integrin-associated protein | — | 2.7 |
M94919 | Beta-globin | — | 2.7, * |
H31897 | Novel | — | −4.4, * |
X16072 | Crybb2, crystallin, beta B2 | −18.0 | — |
U47921 | Cryaa, crystallin, alpha A | −14.5 | — |
X60351 | αB-crystallin | −5.0 | — |
Stress response | | | |
AA998683 | Hspb1, heat shock 27 kDa protein 1 | 2.7, * | 6.2 |
Enzymes | | | |
AA817854 | Cp, ceruloplasmin | — | 5.9 |
AA892775 | Lyz, lysozyme | 3.4, * | 3.8 |
Signal transduction | | | |
L29090 | G protein beta-subunit | — | 4.2, * |
U53184 | Estrogen-responsive uterine mRNA | — | 4.1 |
AI113289 | Protein-tyrosine phosphatase | — | 3.1 |
AA891864 | ATP/GTP binding protein | — | 2.5, * |
Metal and small molecule binding, transporters | | | |
AI176456 | MT2, metallothionein-2 | 3.1 | 3.6 |
M10934 | Retinol-binding protein | — | 3.3, * |
X06916 | p9Ka homologous to calcium-binding protein | — | 2.6 |
M96601 | Slc6a6, solute carrier family 6, member 6 | — | −2.1 |
Growth factors | | | |
M31837 | Igfbp3, insulin-like growth factor binding protein 3 | — | 8.0, * |
L20913 | Vegf, vascular endothelial growth factor form 3 | — | 4.9, * |
AA892559 | Cntf, ciliary neurotropic factor | — | 2.0, * |
Membrane proteins | | | |
AA893280 | Adipose differentiation-related | 2.1 | 5.7, * |
AF097593 | Cdh2, cadherin-2 | — | 2.5, * |
AA874848 | Thy-1 | — | −3.9 |
Cell cycle | | | |
D16308 | Ccnd2, cyclin D2 | — | 6.8, * |
AA859593 | EFP-related, zinc finger, estrogen-induced | — | 6.3 |