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Brian Chon, Mary Qiu, Shan C. Lin; Myopia and Glaucoma in the South Korean Population. Invest. Ophthalmol. Vis. Sci. 2013;54(10):6570-6577. doi: 10.1167/iovs.13-12173.
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© ARVO (1962-2015); The Authors (2016-present)
To examine the association between myopia and glaucoma, visual field defects, optic disc structural damage, and IOP in a population with a high prevalence of normal-tension glaucoma (NTG).
Data were included from 13,433 participants in the 2008 to 2011 Korean National Health and Nutrition Examination Survey, a cross-sectional study. Spherical equivalent was used to define refractive status as emmetropia (−0.99 to 0.99 diopters [D]), mild myopia (−1.00 to −2.99 D), moderate myopia (−3.00 to −5.99 D), severe myopia (<−6 D), and hyperopia (≥+1.00D). Glaucoma was defined by International Society for Geographical and Epidemiological Ophthalmology (ISGEO) criteria.
Compared with those with emmetropia, the odds of a glaucoma diagnosis were higher with moderate myopia (odds ratio [OR] 2.2, 95% confidence interval [CI] 1.2–4.1) and severe myopia (OR 4.6, CI 2.3–9.4). Visual field defects were increased for mild myopia (OR 2.3, CI 1.2–4.5) and severe myopia (OR 20.9, CI 6.3–68.6). Optic disc structural damage was increased for moderate myopia (OR 1.8, CI 1.2–2.5) and severe myopia (OR 2.3, CI 1.5–3.7). Mean IOP was higher for mild myopia (14.4 mm Hg, CI 14.2–14.5 mm Hg), moderate myopia (14.7 mm Hg, CI 14.4–15.0 mm Hg), and severe myopia (14.7 mm Hg, CI 14.3–15.2 mmHg) compared with those with emmetropia (14.0 mm Hg, CI 13.9–14.1 mm Hg).
In South Koreans, more severe myopia was associated with greater odds of glaucoma as defined by ISGEO criteria.
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