December 1973
Volume 12, Issue 12
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Articles  |   December 1973
A Light and Electron Microscopic Study in Serial Sections of Dystrophic Extraocular Muscle Fibers
BRUCE R. PACHTER; JACOB DAVIDOWITZ; GOODWIN M. BREININ
Author Affiliations
  • BRUCE R. PACHTER
    Department of Ophthalmology, New York University School of Medicine, New York University Medical Center, New York, N. Y. 10016.
  • JACOB DAVIDOWITZ
    Department of Ophthalmology, New York University School of Medicine, New York University Medical Center, New York, N. Y. 10016.
  • GOODWIN M. BREININ
    Department of Ophthalmology, New York University School of Medicine, New York University Medical Center, New York, N. Y. 10016.
Investigative Ophthalmology & Visual Science December 1973, Vol.12, 917-923. doi:
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      BRUCE R. PACHTER, JACOB DAVIDOWITZ, GOODWIN M. BREININ; A Light and Electron Microscopic Study in Serial Sections of Dystrophic Extraocular Muscle Fibers. Invest. Ophthalmol. Vis. Sci. 1973;12(12):917-923.

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Abstract

Whole epon-embedded dystrophic extraocular muscles were serially sectioned at 20 microns. These sections were cleared for light microscopy and surveyed for abnormal fibers. Various morphologic disruptions associated with gross changes in diameter over hundreds of microns were observed. Electron microscopic samples reveal a continuum of different kinds of structural changes related to such variations in fiber diameter. These data indicate that a large assortment of ultrastructural changes can occur simultaneously in the same cell.

Copyright 1973 The Association for Research in Vision and Ophthalmology, Inc.
Copyright © 2024 Association for Research in Vision and Ophthalmology.
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