August 1971
Volume 10, Issue 8
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Articles  |   August 1971
Further Electron Microscopic Study of Hereditary Corneal Edema
Author Affiliations
  • ATSUSHI KANAI
    Department of Ophthalmology, College of Medicine, University of Florida, and the Veteran's Administration Hospital, Gainesville, Fla.
  • HERBERT E. KAUFMAN
    Department of Ophthalmology, College of Medicine, University of Florida, and the Veteran's Administration Hospital, Gainesville, Fla.
Investigative Ophthalmology & Visual Science August 1971, Vol.10, 545-554. doi:
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      ATSUSHI KANAI, HERBERT E. KAUFMAN; Further Electron Microscopic Study of Hereditary Corneal Edema. Invest. Ophthalmol. Vis. Sci. 1971;10(8):545-554.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

This report presents further observation on the fine structure of hereditary corneal edema. The anterior and middle stroma showed almost normal collagen lamellar formation. In the posterior stroma irregularity of interfibrillary distance was noted. Cross-sections of collagen fibrils varied in diameter. Two Descemet's membranes were found, the second one contained unusual banded materials. Most parts of the second Descemet's membrane were covered with thickened multiformed packed smaller collagen fibrils, and a fibroblastlike cell layer was present on the face of the anterior chamber. These observations support our earlier study1 which suggested that the morphologic changes occurred during fetal development.

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