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P. J. BENTLEY, OSCAR A. CANDIA; Effects of Some Metabolic Inhibitors on the Electrical Potential Difference and Short-Circuit Current Across the Lens of the Toad Bufo Marinus. Invest. Ophthalmol. Vis. Sci. 1971;10(9):672-676. doi: https://doi.org/.
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The short-circuit current (SCC) across the isolated lens of the toad Bufo marinus can be abolished by iodoacetate or ouabain but is not altered by 2,4-dinitrophenol, acetazolamide, or amiloride. Ethacrynic acid changes the SCC little and not in a manner comparable with that of ouabain. Ouabain and iodoacetate are effective only when placed at the anterior face of the lens from where they also reduce the potential difference (PD).
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