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BRUCE A. ELLINGSEN, W. MORTON GRANT; Influence of Intraocular Pressure and Trabeculotomy on Aqueous Outflow in Enucleated Monkey Eyes. Invest. Ophthalmol. Vis. Sci. 1971;10(9):705-709.
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Quantitative aqueous perfusion was performed at a series of pressures from 5 to 50 mm. Hg in enucleated monkey eyes on which an iridotomy had been performed to minimize artificial changes in depth of the anterior chamber. Total facility of outflow became less when the pressure was increased, similar to what was observed in separately reported experiments on enucleated human eyes. When the pressure was next reduced, total facility tended to increase in monkey eyes, though not in human eyes. Trabeculotomy of one quadrant from within the anterior chamber in monkey eyes made the total facility of outflow several times greater than normal and was calculated to eliminate 83 to 97 per cent of the resistance to outflow in the traheculotomized quadrant.
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