November 1971
Volume 10, Issue 11
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Articles  |   November 1971
Comparative Study of Argon and Ruby Retinal Damage Thresholds
Author Affiliations
  • GEORG D. FRISCH
    Joint AMRDC-AMC Laser Safety Team, Frankford Arsenal, Philadelphia, Pa.
  • EDWIN S. BEATRICE
    Joint AMRDC-AMC Laser Safety Team, Frankford Arsenal, Philadelphia, Pa.
  • ROBERT C. HOLSEN
    Joint AMRDC-AMC Laser Safety Team, Frankford Arsenal, Philadelphia, Pa.
Investigative Ophthalmology & Visual Science November 1971, Vol.10, 911-919. doi:
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      GEORG D. FRISCH, EDWIN S. BEATRICE, ROBERT C. HOLSEN; Comparative Study of Argon and Ruby Retinal Damage Thresholds. Invest. Ophthalmol. Vis. Sci. 1971;10(11):911-919.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The eyes of rhesus monkeys were exposed to argon (514.5 nm.) and ruby (694.3 nm.) laser radiation. Data were obtained using 2.3 to 3 mm. and 7.5 to 8 mm. corneal spot diameters. Retinal exposure sites were examined by ophthalmoscopic and histopathologic techniques. Macular and extramacular exposure sites were separated and analyzed. Probit analysis was utilized in the evaluation of all data and regression lines, and associated confidence intervals were obtained. Utilization of flat preparations of the pigment epithelium and sensory layers of the retina confirmed damage at the lower power levels. Comparable lesions (in terms of ED50 points) were analyzed for the two systems to establish similarities and significant differences.

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