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MONTE G. HOLLAND, MARION STOCKWELL; Sodium Ion Transport of the Ciliary Body in Vitro. Invest. Ophthalmol. Vis. Sci. 1967;6(4):401-409.
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Sodium ion influx and outflux were measured simultaneously, with two radioactive isotopes, in the cat ciliary body isolated in vitro. Measurements of membrane potential or short-circuit current were made concurrently with the isotope studies. In the non-short-circuited membrane, where the membrane electromotive force assisted sodium influx, the sodium ion current was two to three times larger than the estimated average short-circuit current, implying the coexistence of an anion transport. In the continuously short-circuited membrane, in which the membrane electromotive force was eliminated, a net sodium ion influx persisted and was approximately equal to the short-circuit current. Thus, the in vitro cat ciliary body membrane appears to function as a mixed sodium-anion pump in the non-short-circuited state, but mainly as a sodium ion pump when short circuited.
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