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Kenneth N. Ogle, Robert A. Whisnant, Jane B. Hazelrig; Quantitative Study of Pupil Response to Miotic Drugs. Invest. Ophthalmol. Vis. Sci. 1966;5(2):176-185.
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A model by which the time relationship of the miotic effects of three drugs (pilocarpine, eserine, and carbachol) can be described is discussed in a two compartment analysis. The data obtained on six subjects were subjected to a curve-fitting procedure with a computer, from which the parameters of the equation describing the miosis-time curve could be obtained. With these the pertinent characteristics of the responses to the drugs coidd be compared
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