This content is PDF only. Please click on the PDF icon to access.
Abstract
A model by which the time relationship of the miotic effects of three drugs (pilocarpine, eserine, and carbachol) can be described is discussed in a two compartment analysis. The data obtained on six subjects were subjected to a curve-fitting procedure with a computer, from which the parameters of the equation describing the miosis-time curve could be obtained. With these the pertinent characteristics of the responses to the drugs coidd be compared