April 1965
Volume 4, Issue 2
Articles  |   April 1965
Intraocular Pressure Response to Topical Corticosteroids
Author Affiliations
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis, Mo.
Investigative Ophthalmology & Visual Science April 1965, Vol.4, 198-205. doi:https://doi.org/
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      BERNARD BECKER; Intraocular Pressure Response to Topical Corticosteroids. Invest. Ophthalmol. Vis. Sci. 1965;4(2):198-205. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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The intraocular pressure response to topical betamethasone appears to be genetically determined. A study of patients with primary open-angle glaucoma, their relatives, glaucoma suspects, and volunteers shows three populations as to degree of responsiveness. It is suggested that these are the phenotypes which relate to the homozygous poor responder (nn), the heterozygous responder (ng), and the homozygous greater responder (gg).


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