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STUART I. BROWN, BENGT O. HEDBYS; The Effect of Ouabain on the Hydration of the Cornea. Invest. Ophthalmol. Vis. Sci. 1965;4(2):216-221.
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The effect of ouabain on the hydration of the rabbit cornea has been studied. The glycoside was found to prevent the dehydration of the cornea during temperature reversal procedures and its application to the cornea in vivo results in significant corned, swelling. A comparison of the effect of ouabain on the cornea to the drug's effect on electrolyte transport systems in the tissues suggests that the cornea regulates its hydration by a transport of electrolytes, presumably across the endothelium.
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