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Abstract
Utilization of 35S-sulfate by the retina of the rat was studied by both autoradiographic and biochemical techniques. One day after the intraperitoneal injection of the labeled sulfate in 7-week-old animals, radioactivity was present in significant amounts in the plexiform layers of the retina, and was particularly concentrated in the inner segments of the photoreceptors. Biochemical analysis showed that, although mucopolysaccharides constituted less than 5 per cent of the retinal dry weight, essentially all of the bound 35S could be recovered in this fraction.