February 1964
Volume 3, Issue 1
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Articles  |   February 1964
The Fine Structure of the Cornea in Fuchs' Endothelial Dystrophy
Author Affiliations
  • JACK KAYES
    Department of Ophthalmology, Washington University School of Medicine, St. Louis, Mo., Department of Anatomy, Karolinska Institute, Stockholm, Sweden
  • AKE HOLMBERG
    Department of Ophthalmology, Washington University School of Medicine, St. Louis, Mo., Department of Anatomy, Karolinska Institute, Stockholm, Sweden
Investigative Ophthalmology & Visual Science February 1964, Vol.3, 47-67. doi:https://doi.org/
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      JACK KAYES, AKE HOLMBERG; The Fine Structure of the Cornea in Fuchs' Endothelial Dystrophy. Invest. Ophthalmol. Vis. Sci. 1964;3(1):47-67. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The electron microscopic appearance of normal human cornea is described. The changes from the normal in Fuchs' endothelial dystrophy are shown in electron micrographs. The endothelium becomes thin and, distorted, in shape and filled, with vacuoles. Descemet's membrane becomes markedly thickened, changes its smooth surface, and, its component ultrastructural units become distinctly different. The course of these changes is charted and, an attempt is made to correlate them with the light microscopic appearance and the pathophysiology involved.

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