April 1964
Volume 3, Issue 2
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Articles  |   April 1964
Retinal Microcirculation in vivo
Author Affiliations
  • EPHRAIM FRIEDMAN
    Howe Laboratory of Ophthalmology, Harvard Medical School Eye Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Mass.
  • TAYLOR R. SMITH
    Howe Laboratory of Ophthalmology, Harvard Medical School Eye Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Mass.
  • TOICHIRO KUWABARA
    Howe Laboratory of Ophthalmology, Harvard Medical School Eye Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Mass.
  • SUSAN MIMURA
    Howe Laboratory of Ophthalmology, Harvard Medical School Eye Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Mass.
Investigative Ophthalmology & Visual Science April 1964, Vol.3, 217-226. doi:
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      EPHRAIM FRIEDMAN, TAYLOR R. SMITH, TOICHIRO KUWABARA, SUSAN MIMURA; Retinal Microcirculation in vivo. Invest. Ophthalmol. Vis. Sci. 1964;3(2):217-226.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

A method is described which makes possible the direct microscopic observation of the living retinal microcirculation inthe relatively intact globe of animals at magnifications up to x1,000. Observations have been made on acute preparations and repeated after intervals as long as six weeks. Observations have been documented in photomicrographs and cinephotographs.Under the conditions of the experiment the flow of blood in the microvascular bed of the retina is characterized by its steadiness and high linear velocity. The capillaries appear to be akoays open to the flow of erythrocytes.

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