December 1963
Volume 2, Issue 6
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Articles  |   December 1963
An Electron Microscope Study of Rhabdomyosarcoma
Author Affiliations
  • GEORGE B. CHAPMAN
    Department of Anatomy, Cornell University Medical College, New York Institute of Ophthalmology, Columbia-Presbyterian Medical Center, New York, N. Y.
  • IRA S. JONES
    Department of Anatomy, Cornell University Medical College, New York Institute of Ophthalmology, Columbia-Presbyterian Medical Center, New York, N. Y.
  • WALTER W. SPELSBERG
    Department of Anatomy, Cornell University Medical College, New York Institute of Ophthalmology, Columbia-Presbyterian Medical Center, New York, N. Y.
Investigative Ophthalmology & Visual Science December 1963, Vol.2, 538-557. doi:
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      GEORGE B. CHAPMAN, IRA S. JONES, WALTER W. SPELSBERG; An Electron Microscope Study of Rhabdomyosarcoma. Invest. Ophthalmol. Vis. Sci. 1963;2(6):538-557.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

An electron microscope study of ultrathin sections of two rhabdomyosarcomas revealed the presence of cytologic characteristics previously described in neoplasias: nuclear envelope invagination, reduction in number of organelles, reduced size of mitochondria, stoollen mitochondria. In addition, one group of seven centrioles was observed and many cells revealed the presence of aggregates of small, dense particles. Groups of fibrous structures were occasionally encountered.

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