August 1962
Volume 1, Issue 4
Articles  |   August 1962
Therapy of Experimental Herpes Simplex Keratitis
Author Affiliations
    Massachusetts Eye and Ear Infirmary, Boston, Mass.; Present address, J. Hillis Miller Health Center, University of Florida, Gainesville, Fla.
    Massachusetts Eye and Ear Infirmary Boston, Mass.
Investigative Ophthalmology & Visual Science August 1962, Vol.1, 561-564. doi:
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      HERBERT E. KAUFMAN, GEORGE M. HOWARD; Therapy of Experimental Herpes Simplex Keratitis. Invest. Ophthalmol. Vis. Sci. 1962;1(4):561-564.

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      © ARVO (1962-2015); The Authors (2016-present)

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Topical therapy with trypsin, chymotrypsin, and monoxychloroserene, and corneal scrub with iodine, ether, and silver nitrate did not demonstrably reduce the incidence of a positive virus culture from rabbit corneas infected with herpes simplex. It is suggested that the virucidal properties of such substances as measured by their effect on cell-free virus suspensions is not pertinent to the abolition of infection from primary experimental dendritic keratitis, and may not be an important consideration in the therapy of this condition.


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