We also compared the ppRPE/BM shape of the posttreatment SD-OCT images from group C to that of normal subjects. The controls had a negative review of systems (including questions about chronic headaches, diplopia, and tinnitus) and a normal ophthalmic examination finding that specifically excluded subjects with abnormal visual acuity, color vision, pupil examination findings, intraocular pressure, visual fields, or ophthalmoscopic findings; or SD-OCT evidence of an optic neuropathy, edema, optic atrophy, glaucoma, or disc anomalies (e.g., drusen, hypoplasia, oblique insertion, tilting, high myopia, staphylomas, or otherwise dysplastic).
This study was approved by the SUNY Stony Brook Committee on Research Involving Humans and the New York Eye and Ear Infirmary Institutional Review Board.
The methodology used here, as well as studies on validation, reproducibility, and artifacts, has been previously published
16 and adheres to the provisions of the Declaration of Helsinki. We will provide a brief summary specific to this study below.