Purchase this article with an account.
Naoko Onizuka, Masafumi Uematsu, Kiyoshi Suzuma, Takashi Kitaoka; Correlation of retina circulation and blood pressure before and after panretinal photocoagulation for diabetic retinopathy. Invest. Ophthalmol. Vis. Sci. 2014;55(13):1070.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To investigate the correlation of retina blood flow and blood pressure before and after panretinal photocoagulation (PRP) for diabetic retinopathy (DR).
This study was conducted in 21 eyes of 21 patients. Retinal blood flow at the optic disc was evaluated as mean blur rate (MBR) by laser speckle flowgrathy (LSFG) and PRP was performed using a pattern scanning laser (PASCAL). The mean aortic pressure (MAP) and the ocular perfusion pressure are determined by the following equation. MAP= diastolic pressure + 1/3(systolic pressure-diastolic pressure). Ocular perfusion pressure= 2/3 MAP - intraocular pressure (IOP). The correlations among retinal blood velocity, the ocular perfusion pressure, MAP, and IOP were investigated the before and 6months after PRP.
Before PRP, the equilateral correlation was seen in the MAP and the retinal blood flow ( r=0.5871, P=0.0026), the ocular perfusion pressure and the retinal blood flow (r=0.5584, P=0.0043). In contrast, 6months after PRP, the MAP and the retinal blood flow were not significantly correlated (r=0.3712, P=0.0535), and the ocular perfusion pressure and the retinal blood flow became weak (r=0.4586, P=0.021
Mean blood velocity significantly correlated with the blood pressure and ocular perfusion pressure before PRP. The other hands, 6months after PRP, the equilateral correlation of the MAP and the retinal blood flow disappeared.
This PDF is available to Subscribers Only