Abstract
Purpose:
To compare the posture change on intraocular pressure (IOP) and analysis the relationship to ocular and systemic factors in healthy subjects.
Methods:
Forty-one healthy subjects were included, 26 females and 15males. The underlying ocular and systemic factors were taken before the IOP measurement, such as objective refractive status, height, weight and blood pressure. Accupen was used in both eyes of each subject. From 5:30pm to 7:30pm, IOP was measured in a random order of sitting, supine, right lateral and left lateral position. Each position was maintained at least 5 minutes. Wilcox on signed-rank test was used to compare IOP alterations. Pearson’s correlation analyses its relationship to ocular and systemic factors. P values of less than 0.05 were considered to be significant.
Results:
The mean age was 49.17±9.72 years old. And the CCT was 540.59±28.07um in right eye and 543.76±28.27um in left. No significant difference was found between right and left eye in IOP of different position and the IOP changes(P>0.05).Hence, the right eyes were evaluated only to illustrate our observations. The IOP increased significantly from sitting to supine(11.30±2.63mmHg& 12.44±3.27 mmHg, P<0.001). Compared with supine position, the dependent eye (14.32±3.25 mmHg, right lateral position) and non-dependent eye(13.70±2.71 mmHg, left lateral position) increased significantly. The IOP change between sitting and right lateral position was up to 3.01±2.73 mmHg(P<0.0001). In Pearson’s analysis, positive correlation was found between age and IOP change( supine-right lateral, sitting-right lateral position),and IOP in right lateral position(r=0.389,P<0.05 ; r=0.475, P<0.05; r=0.513,P<0.001).No correlation was found between age and IOP in sitting and supine, as well as the IOP change of sitting-supine( P>0.05 ).There were no correlations between different body position IOP and BMI(weight /height 2), refractive status, as well as systolic and diastolic blood pressure(P>0.05).
Conclusions:
IOP was gradually increased in the order of sitting, supine, lateral position. And with the age increasing, the IOP change regard to lateral position enlarged.
Keywords: 568 intraocular pressure