April 2014
Volume 55, Issue 13
Free
ARVO Annual Meeting Abstract  |   April 2014
POSTURAL INTRAOCULAR PRESSURE CHANGES IN EYES WITH NORMAL TENSION GLAUCOMA WITHOUT OCULAR HYPOTENSIVE AGENTS AND HEALTHY CONTROL EYES
Author Affiliations & Notes
  • Hiroki Tanaka
    Gifu University Graduate School of Medicine, Gifu, Japan
  • Akira Sawada
    Gifu University Graduate School of Medicine, Gifu, Japan
  • Tetsuya Yamamoto
    Gifu University Graduate School of Medicine, Gifu, Japan
  • Footnotes
    Commercial Relationships Hiroki Tanaka, None; Akira Sawada, None; Tetsuya Yamamoto, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science April 2014, Vol.55, 117. doi:
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      Hiroki Tanaka, Akira Sawada, Tetsuya Yamamoto; POSTURAL INTRAOCULAR PRESSURE CHANGES IN EYES WITH NORMAL TENSION GLAUCOMA WITHOUT OCULAR HYPOTENSIVE AGENTS AND HEALTHY CONTROL EYES. Invest. Ophthalmol. Vis. Sci. 2014;55(13):117.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To compare the posture-induced intraocular pressure (IOP) changes in eyes with normal tension glaucoma (NTG) and healthy control eyes with normal IOPs.

Methods: IOP was measured in the sitting and the lateral decubitus position with an Icare rebound tonometer (Icare). The IOP in the lateral decubitus position was measured in the upper-eyes 5 minutes after assuming this posture.

Results: Age-, and gender-matched eighty patients with NTG and 80 controls with normal IOPs were studied. The mean age was 54.9 ± 12.0 years in the NTG group and 56.3 ± 11.8 years in the control group. Men were 37 and women were 43 in each group. The mean IOP measured with the Goldmann applanation tonometer was 13.0 ± 2.1 mmHg in the NTG eyes and 13.1 ± 2.7 mmHg in the control eyes (P=0.720). The IOP in the sitting position measured with the Icare tonometer was 14.6 ± 3.0 mmHg in eyes with NTG and 14.4 ± 3.6 mmHg in eyes with normal IOPs (P=0.807). The IOP in the lateral decubitus position was significantly increased to 18.3 ± 3.1 mmHg in eyes with NTG and 18.0 ± 3.8 mmHg in eyes with normal IOPs (P<0.001 in both groups; vs. baseline). The postural IOP difference was +3.8 ± 2.0 mmHg in NTG eyes and +3.5 ± 2.0 mmHg in normal eyes, and these increases were not significantly different between the two groups (P=0.496).

Conclusions: Postural IOP changes are comparable among eyes with NTG without ocular hypotensive medications and control eyes.

Keywords: 568 intraocular pressure  
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