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Hiroki Tanaka, Akira Sawada, Tetsuya Yamamoto; POSTURAL INTRAOCULAR PRESSURE CHANGES IN EYES WITH NORMAL TENSION GLAUCOMA WITHOUT OCULAR HYPOTENSIVE AGENTS AND HEALTHY CONTROL EYES. Invest. Ophthalmol. Vis. Sci. 2014;55(13):117. doi: https://doi.org/.
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To compare the posture-induced intraocular pressure (IOP) changes in eyes with normal tension glaucoma (NTG) and healthy control eyes with normal IOPs.
IOP was measured in the sitting and the lateral decubitus position with an Icare rebound tonometer (Icare). The IOP in the lateral decubitus position was measured in the upper-eyes 5 minutes after assuming this posture.
Age-, and gender-matched eighty patients with NTG and 80 controls with normal IOPs were studied. The mean age was 54.9 ± 12.0 years in the NTG group and 56.3 ± 11.8 years in the control group. Men were 37 and women were 43 in each group. The mean IOP measured with the Goldmann applanation tonometer was 13.0 ± 2.1 mmHg in the NTG eyes and 13.1 ± 2.7 mmHg in the control eyes (P=0.720). The IOP in the sitting position measured with the Icare tonometer was 14.6 ± 3.0 mmHg in eyes with NTG and 14.4 ± 3.6 mmHg in eyes with normal IOPs (P=0.807). The IOP in the lateral decubitus position was significantly increased to 18.3 ± 3.1 mmHg in eyes with NTG and 18.0 ± 3.8 mmHg in eyes with normal IOPs (P<0.001 in both groups; vs. baseline). The postural IOP difference was +3.8 ± 2.0 mmHg in NTG eyes and +3.5 ± 2.0 mmHg in normal eyes, and these increases were not significantly different between the two groups (P=0.496).
Postural IOP changes are comparable among eyes with NTG without ocular hypotensive medications and control eyes.
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